mitobridge acquisition

The amount will be adjusted depending on the cash and cash equivalents etc. Nothing contained herein should be considered a solicitation, promotion or advertisement for any drug including those under development. The achievements resulting from the collaboration have exceeded our expectations including the rapid advancement of multiple programs," commented Yoshihiko Hatanaka, President and CEO, Astellas. The amount will be adjusted depending on the cash and cash equivalents etc. held by Mitobridge is $161.7 million. The achievements resulting from the collaboration have exceeded our expectations including the rapid advancement of multiple programs," commented Yoshihiko Hatanaka, President and CEO, Astellas. This website is intended for U.S. residents only. In addition, Mitobridge shareholders will be eligible for additional payments from Astellas that total up to $225 million2 depending on the progress of various programs in clinical development. By using this site, you accept our use of cookies as described in our privacy policy. If you are not a reporter and need assistance, please visit our contact us page that includes information for patients, healthcare providers and researchers. Information about pharmaceutical products (including products currently in development) which is included in this press release is not intended to constitute an advertisement or medical advice. We are also creating new value by combining internal capabilities and external expertise in the medical/healthcare business. (3) Payment: Cash on hand For media inquiries and reporter requests, please click here to fill out a request form. At this point, Astellas will maintain the organization in Cambridge, MA, and retain the Mitobridge name as a division of Astellas. November 02, 2022 08:04 AM Eastern Daylight Time PALO ALTO, Calif.-- ( BUSINESS WIRE )--OrsoBio, Inc., a clinical-stage biopharmaceutical company developing treatments for severe metabolic. In addition, Mitobridge shareholders will be eligible for additional payments from Astellas that total up to $225 million depending on the progress of various programs in . The amount will be adjusted depending on the cash and cash equivalents etc. Acquisition Analysis Whilst multi-system involvement is often evident, neurological manifestation is the principal presentation in most cases. We are also creating new value by combining internal capabilities and external expertise in the medical/healthcare business. When typing in this field, a list of search results will appear and be automatically updated as you type. Mitobridge will become a wholly-owned subsidiary of Astellas following the close of the acquisition. We are capitalizing on the latest biological findings that have . held by Mitobridge is $161.7 million. Any information on the products contained herein is not intended to provide medical advice nor should be used as a substitute for the advice provided by your physician or other healthcare provider. The current survey provides an important benchmark. We focus on Urology, Oncology, Immunology, Nephrology and Neuroscience as prioritized therapeutic areas while advancing new therapeutic areas and discovery research leveraging new technologies/modalities. Acquired by Astellas Pharma Cambridge, Massachusetts, United States 11-50 Series A Private www.mitobridge.com/ 73,059 Highlights Total Funding Amount $5.2M Contacts 6 Employee Profiles 2 Investors 3 Similar Companies 9 Recent News & Activity (2) As Astellas is a shareholder in Mitobridge, the actual payment by Astellas to Mitobridge will be $165.5 million. (1) Corporate Name: Mitobridge, Inc. (2) As Astellas is a shareholder in Mitobridge, the actual payment by Astellas to Mitobridge will be $165.5 million. (2) Location: Cambridge, MA At this point, Astellas will maintain the organization in Cambridge, MA, and retain the Mitobridge name as a division of Astellas. ", "We at Mitobridge are delighted to become part of Astellas' major initiative to develop new therapies for serious diseases. The company will share preclinical data at The Liver Meeting. $225 million* to make Mitobridge a wholly-owned subsidiary of Astellas (4) Amount: "Mitobridge as a subsidiary of Astellas will now have additional resources to continue to advance and expand on its achievements to date.". Astellas is on the forefront of healthcare change to turn innovative science into value for patients. Mitobridge will be eligible for additional payments that total up to $225 million2, depending on the progress of various programs in clinical development. held by Mitobridge is $161.7 The amount is subject to further true-up based on actual numbers as of the closing date. Astellas is on the forefront of healthcare change to turn innovative science into value for patients. About Mitobridge (fka Mitokyne)Mitobridge is discovering and developing small molecule therapeutics that enhance mitochondrial function and that build upon the emerging scientific findings linking mitochondrial dysfunction with disease pathologies. These statements are based on management's current assumptions and beliefs in light of the information currently available to it and involve known and unknown risks and uncertainties. Mitobridge, Inc. Subsidiary Company Acquisition Overview Free sign up to view the full data Summary This table shows a brief introduction of acquisition situation of the company and its subsidiaries respectively. If you are not a reporter and need assistance, please visit our contact us page that includes information for patients, healthcare providers and researchers. PALO ALTO, Calif., November 02, 2022--OrsoBio acquired an ACMSD inhibitor program from Mitobridge, an Astellas Company. The company will share preclinical data at The Liver Meeting. Cautionary NotesIn this press release, statements made with respect to current plans, estimates, strategies and beliefs and other statements that are not historical facts are forward-looking statements about the future performance of Astellas. -- Company to share preclinical data on TLC-065 at The Liver Meeting--. For more information, please visit our website at https://www.astellas.com/en. About Astellas Conclusions. About AstellasAstellas Pharma Inc., based in Tokyo, Japan, is a company dedicated to improving the health of people around the world through the provision of innovative and reliable pharmaceutical products. PALO ALTO, Calif.-- (BUSINESS WIRE)-- OrsoBio, Inc., a clinical-stage biopharmaceutical company developing treatments for severe metabolic disorders, today announced its acquisition of an ACMSD. This is Astellas Pharma's 6th largest (disclosed) transaction. On December 1, 2017, Astellas Pharma acquired life science company Mitobridge for 166M USD Acquisition Highlights. PALO ALTO, Calif., November 02, 2022--OrsoBio acquired an ACMSD inhibitor program from Mitobridge, an Astellas Company. Such factors include, but are not limited to: (i) changes in general economic conditions and in laws and regulations, relating to pharmaceutical markets, (ii) currency exchange rate fluctuations, (iii) delays in new product launches, (iv) the inability of Astellas to market existing and new products effectively, (v) the inability of Astellas to continue to effectively research and develop products accepted by customers in highly competitive markets, and (vi) infringements of Astellas' intellectual property rights by third parties. Mitobridge is developing drug candidates that are directed at multiple points in the NAD+biosynthetic and metabolic pathway. Building upon the emerging scientific findings linking mitochondrial dysfunction with disease pathologies, we are progressing innovative approaches to the treatment of diseases with high unmet medical need. Under the 2013 partnership agreements, Astellas and Mitobridge have collaborated to discover and develop compounds that target mitochondrial function. Astellas is on the forefront of healthcare change to turn innovative science into value for patients. OrsoBio, Inc., a clinical-stage biopharmaceutical company developing treatments for severe metabolic disorders, today announced its acquisition of an ACMSD inhibitor program from Mitobridge, an Astellas Company. Information about pharmaceutical products (including products currently in development) which is included in this press release is not intended to constitute an advertisement or medical advice. Sorry, you need to enable JavaScript to visit this website. "Through the acquisition of Mitobridge, Astellas accelerates our investment in diseases caused by mitochondria dysfunctions in order to deliver innovative new treatment options to patients. NAD+ repletion improves muscle function in muscular dystrophy and counters global PARylation. The Company is progressing innovative approaches to the treatment of diseases with high unmet medical need with the strategy to establish proof of concept in rare diseases and then expand into more common diseases. The site uses cookies to provide you with a more responsive and personalized service and to analyze site traffic. As Astellas is a shareholder in Mitobridge, the actual payment by Astellas to Mitobridge shareholders after adjustment based on the estimate of cash and cash equivalents etc. For media inquiries and reporter requests, please click here to fill out a request form. The largest life science acquisition in 2017 was Actelion - which was acquired by Johnson & Johnson for $30.0B. Mitobridge will be eligible for additional payments that total up to $225 million2, depending on the progress of various programs in clinical development. Japanese company Astellas Pharma has concluded the acquisition of 100% equity in US-based biotechnology firm Mitobridge for a total of $225m, making the firm its wholly owned subsidiary. This website contains information about products that may not be available in all countries, or may be available under different trademarks, for different indications, or in different dosages. MA-0211, the most advanced program emerging from the collaboration, is currently in Phase 1 clinical studies for Duchenne Muscular Dystrophy (DMD). Under the terms of the agreements, Galapagos is to acquire all outstanding shares of CellPoint and AboundBio in an all-cash transaction against payment of an upfront amount of 125 million for. Mitobridge will become a wholly-owned subsidiary of Astellas following the close of the acquisition. TOKYO, Jan. 23, 2018 /PRNewswire/ -- Astellas Pharma Inc. (TSE: 4503, President and CEO: Yoshihiko Hatanaka, "Astellas" ) today announced that it has completed the acquisition of Mitobridge, Inc. ("Mitobridge"), and Mitobridge has become a wholly owned subsidiary ofAstellas as of January 23, 2018 (U.S. Eastern Time). Astellas Cautionary NotesIn this press release, statements made with respect to current plans, estimates, strategies and beliefs and other statements that are not historical facts are forward-looking statements about the future performance of Astellas. Mitobridge, Inc. is a developer of small molecule therapeutics that enhance mitochondrial function and that build upon the emerging scientific findings linking mitochondrial dysfunction with disease pathologies. A number of factors could cause actual results to differ materially from those discussed in the forward-looking statements. By exercising the option right to acquire Mitobridge, Astellas paid $225 million1 to acquire 100% of the equity in Mitobridge. Mitobridge shareholders will potentially receive additional payments of up to $225m from Astellas based on the progress of clinical development programmes. The amount assumes the current Astellas' shares on a fully diluted basis. Get the latest Pittsburgh local news, breaking news, sports, entertainment, weather and traffic, as well as national and international news, from the Pulitzer Prize-winning staff of the Pittsburgh Post-Gazette. One day out of stealth, Yale University spinout, OrsoBio, announces an acquisition of an ACMSD inhibitor program from Mitobridge, Inc., an Astellas Pharma US company to address metabolic and . In addition, Mitobridge shareholders will be eligible for additional payments from Astellas that total up to $225 million(2) depending on the progress of various programs in clinical development. Sorry, you need to enable JavaScript to visit this website. For more information, please visit our website at https://www.astellas.com/en. TOKYO, Jan. 23, 2018 /PRNewswire/ -- Astellas Pharma Inc. (TSE: 4503, President and CEO: Yoshihiko Hatanaka, "Astellas" ) today announced that it has completed the acquisition of Mitobridge, Inc. ("Mitobridge"), and Mitobridge has become a wholly owned subsidiary ofAstellas as of January 23, 2018 (U.S. Eastern Time). Mitochondrial DNA makes up only 0.1% of the overall human genome and is passed down exclusively from mother to child. This is Astellas Pharma's 6th transaction in the Life Science sector. In this press release, statements made with respect to current plans, estimates, strategies and beliefs and other statements that are not historical facts are forward-looking statements about the future performance of Astellas. 2022112OrsoBio 1MitobridgeACMSD 2Phenex LXR TLC-27163"Shionogi"ACC2 TLC-3595S-7235954 . Top Contributing Subsidiaries This chart shows the distribution of the subsidiaries' acquisition. Any information on the products contained herein is not intended to provide medical advice nor should be used as a substitute for the advice provided by your physician or other healthcare provider. (1) The name of Mitokyne, Inc. was changed to Mitobridge, Inc. TOKYO, Jan. 23, 2018 /PRNewswire/ -- Astellas Pharma Inc. today announced that it has completed the acquisition of Mitobridge, Inc. , and Mitobridge has become a wholly owned subsidiary. Coenzyme Q (CoQ) lipids are ancient electron carriers that, in eukaryotes, function in the mitochondrial respiratory chain. | August 13, 2022 By exercising the option right to acquire Mitobridge, Astellas paid $225 million1 to acquire 100% of the equity in Mitobridge. By exercising the option right according to the amended agreement, Astellas will pay an upfront fee of $225 million2 to acquire Mitobridge. By using this site, you accept our use of cookies as described in our privacy policy. Astellas Acquires Mitobridge Under Existing Collaboration, - Accelerating the Discovery and Development of Novel Drugs that Target Mitochondrial Functions -, For further information: Astellas Pharma Inc., Corporate Communications, TEL: +81-3-3244-3201 FAX: +81-3-5201-7473, California Declaration of Comprehensive Compliance Program, Vermonts Pharmaceutical Marketer Price Disclosure, Wholesale Acquisition Cost Information for Colorado Prescribers, Consumer Product Safety Commission Regulations, Understanding the Gastric and GEJ Cancer Landscape. Discovery Company profile page for Mitobridge, Inc. including technical research,competitor monitor,market trends,company profile& stock symbol Mitobridge is discovering and developing small molecule therapeutics that enhance mitochondrial function and that build upon the emerging scientific findings linking mitochondrial dysfunction with disease pathologies. Mitobridge will be eligible for additional payments that total up to $225 million (2), depending on the progress of various programs in clinical development. It features multiple consultations and tests, and, often, conflicting diagnoses. OrsoBio, Inc., a clinical-stage biopharmaceutical company developing treatments for severe metabolic disorders, today announced its acquisition of an ACMSD inhibitor program from Mitobridge, an . Please read our privacy policy for more information on the cookies we use, the processing of your personal data and how to delete or block the use of cookies. OrsoBio Announces Acquisition of LXR Inverse Agonist Program for Treatment of Severe Dyslipidemias from Phenex Pharmaceuticals November 2, 2022 . In addition, Mitobridge shareholders will be eligible for additional payments from Astellas that total up to $225 million 2 depending on the progress of various programs in clinical development. TOKYO and CAMBRIDGE, Mass., Nov. 30, 2017 /PRNewswire/ -- Astellas Pharma Inc. (TSE: 4503, President and CEO: Yoshihiko Hatanaka, "Astellas") and Mitobridge, Inc.1 (President and CEO: Kazumi Shiosaki, "Mitobridge") today announced that Astellas has exercised its exclusive option right to acquire Mitobridge under the amended terms of the October 2013 partnership agreement governing an R&D collaboration focused on discovering and developing novel drugs that target mitochondrial function. In addition, Mitobridge shareholders will be eligible for. We are grateful for the tremendous support and guidance from Astellas, MPM Capital, and Longwood Fund that enabled Mitobridge to rapidly build an exciting pipeline," said Kazumi Shiosaki, Ph.D., President & CEO, and co-founder of Mitobridge. A number of factors could cause actual results to differ materially from those discussed in the forward-looking statements. By exercising the option right to acquire Mitobridge, Astellas paid $225 million1 to acquire 100% of the equity in Mitobridge. Astellas is on the forefront of healthcare change to turn innovative science into value for patients. Founded in 2013 Private Company "Mitobridge is discovering and developing novel therapeutics that improve mitochondrial functions. The closing of the acquisition is subject to customary regulatory approvals, and is expected to be finalized in the next several weeks. Nothing contained herein should be considered a solicitation, promotion or advertisement for any drug including those under development. The Company was founded in 2011 with seed financing from MPM Capital. The amount will be adjusted depending on the cash and cash equivalents etc. (6) Relationship with Astellas: Equity-method affiliate, research and development partner. Please read our privacy policy for more information on the cookies we use, the processing of your personal data and how to delete or block the use of cookies. The transaction accelerates Astellas' research and development in diseases associated with mitochondrial dysfunctions and will enable the delivery of innovative new treatment options to patients. The company will share preclinical data at The Liver Meeting. These drug candidates have the potential to treat genetic, metabolic or neurodegenerative disorders as well as conditions of aging. These reflect disease variety, diagnostic uncertainty, and clinician unfamiliarity. By exercising the option right to acquire Mitobridge, Astellas paid $225 million(1) to acquire 100% of the equity in Mitobridge. In addition, Mitobridge shareholders will be eligible for additional payments from Astellas that total up to $225 million2 depending on the progress of various programs in clinical development. In addition, Mitobridge shareholders will be eligible for additional payments from Astellas that total up to $225 million2 depending on the progress of various programs in clinical development. from 8 AM - 9 PM ET. About Astellas 3m ago Astellas Completes Acquisition of Mitobridge, Inc. November 30, 2017 Astellas Acquires Mitobridge Under Existing Collaboration November 6, 2017 Mitobridge Presents Preclinical Data Demonstrating Beneficial Effects of PPAR Modulators in Acute Kidney Injury at American Society of Nephrology Annual Meeting September 18, 2017 PPAR Promotes Running Endurance by Preserving Glucose. Astellas Pharma, Inc. has snapped up its exclusive option to buy out the biotech Mitobridge, Inc. in a deal worth up to $450 million. Mitobridge Inc. was founded in 2013 with financing from MPM Capital, Longwood Fund, and Astellas Pharma's Venture Management team, all sharing a vision for the promise of mitochondrial-targeted therapeutics. Astellas Completes Acquisition of Mitobridge, Inc. For further information: Contacts for inquiries or additional information: Astellas Pharma Inc., Corporate Communications, TEL: +81-3-3244-3201 FAX: +81-3-5201-7473, California Declaration of Comprehensive Compliance Program, Vermonts Pharmaceutical Marketer Price Disclosure, Wholesale Acquisition Cost Information for Colorado Prescribers, Consumer Product Safety Commission Regulations, Understanding the Gastric and GEJ Cancer Landscape. (5) Expected timing of closing: Next several weeks, subject to customary regulatory approvals, Overview of Acquired Company(1) Corporate Name: Mitobridge, Inc.(2) Location: Cambridge, MA(3) Representative: President & CEO Kazumi Shiosaki(4) Founded year: 2011(5) Number of employees: 27(6) Relationship with Astellas: Equity-method affiliate, research and development partner. age-associated conditions. The Company was founded in 2011 with seed financing from MPM Capital. By exercising the option right to acquire Mitobridge, Astellas paid $225 million1 to acquire 100% of the equity in Mitobridge. Environmental, Social and Governance (ESG), HVAC (Heating, Ventilation and Air-Conditioning), Machine Tools, Metalworking and Metallurgy, Aboriginal, First Nations & Native American. PALO ALTO, Calif.- (BUSINESS WIRE)- #TLM22 -OrsoBio, Inc., a clinical-stage biopharmaceutical company developing treatments for severe metabolic disorders, today announced its acquisition of an ACMSD inhibitor program from Mitobridge, an Astellas Company. FutureWise Research has released a research report that analyses Kearns-Sayre Syndrome Market trends in order to forecast market. (3) Representative: President & CEO Kazumi Shiosaki These drug candidates have the potential to treat genetic, metabolic or neurodegenerative . -- Company to share preclinical data on TLC-065 at The Liver Meeting --PALO ALTO, Calif.--(BUSINESS WIRE)--#TLM22--OrsoBio, Inc., a clinical-stage biopharmaceutical company developing treatments for severe metabolic disorders, today announced its acquisition of an ACMSD inhibitor program from Mitobridge, an Astellas Company. Astellas Cautionary Notes Astellas Completes Acquisition of Mitobridge, Inc. Mitobridge Adds NAD Modulation as a Therapeutic Approach for Improving Mitochondrial Function, Mitobridge Announces Sponsored Research Agreement to Evaluate PPAR Compounds in Cells from Patients with Mitochondrial Disease, Mitobridge Secures Key Intellectual Property from the Salk Institute, Astellas and Mitokyne to Pursue Mitochondria-Related Disease Therapies, 63rd American Society of Hematology (ASH) Annual Meeting, American Chemical Society (ACS) Meeting Fall 2021, American Society of Nephrology (ASN) Kidney Week 2019; Washington, DC, Poster Presentation ASN Conference, San Diego, October 2018, Mitobridge Poster presentation at American Chemical Society Meeting, Boston, August 2018, American Society of Nephrology (ASN) Kidney Week 2017; New Orleans, LA, INFORM: International Network for Fatty Acid Oxidation Research and Management; Rio de Janeiro, Brazil, Medicinal Chemistry: Gordon Research Conference; New London, NH, PPMD: 2017 Connect Conference; Chicago, IL, UMDF: 2017 Scientific Program Mitochondrial Medicine; Washington, DC, Euromit 2017: International Meeting on Mitochondrial Pathology; Cologne, Germany, Targeting acute kidney injury in COVID-19, Addressing hERG activity while maintaining favorable potency, selectivity and pharmacokinetic properties of PPAR modulators, Mitobridge; Highly selective peroxisome proliferator-activated receptor d (PPARd) modulator demonstrates improved safety profile compared to GW501516, Mitobridge; Selective PPAR Modulators Improve Mitochondrial Function:Potential Treatment for Duchenne Muscular Dystrophy (DMD), Mitobridge; Novel highly selective inhibitors of ubiquitin specific protease 30 (USP30) accelerate mitophagy, Mitobridge; Novel highly selective peroxisome proliferator-activated receptor d (PPARd) modulators with pharmacokinetic properties suitablefor once-daily oral dosing, Discovery and characterization of selective small molecule inhibitors of the mammalian mitochondrial division dynamin, DRP1, Novel highly selective peroxisome proliferator-activated receptor (PPAR) modulators with pharmacokinetic properties suitable for once-daily oral dosing, A Novel Mitophagy Assay for Skeletal Myotubes. In October 2013, it closed a Series A financing from MPM Capital, Longwood Fund, and Astellas Pharma and a shared vision for the promise of mitochondrial-targeted therapeutics. Astellas Pharma Inc., based in Tokyo, Japan, is a company dedicated to improving the health of people around the world through the provision of innovative and reliable pharmaceutical products. Cision Distribution 888-776-0942 As Astellas is a shareholder in Mitobridge, the actual payment by Astellas to Mitobridge shareholders will be $165.5 million. Acquisition Summary OrsoBio Acquires ACMSD Inhibitor Program to Address Mitochondrial Dysfunction from Mitobridge, an Astellas Company Wednesday, November 02, 2022 OrsoBio, Inc., a clinical-stage biopharmaceutical company developing treatments for severe metabolic disorders, today announced its acquisition of an ACMSD inhibitor program from Mitobridge, an Astellas . These statements are based on management's current assumptions and beliefs in light of the information currently available to it and involve known and unknown risks and uncertainties. Such factors include, but are not limited to: (i) changes in general economic conditions and in laws and regulations, relating to pharmaceutical markets, (ii) currency exchange rate fluctuations, (iii) delays in new product launches, (iv) the inability of Astellas to market existing and new products effectively, (v) the inability of Astellas to continue to effectively research and develop products accepted by customers in highly competitive markets, and (vi) infringements of Astellas' intellectual property rights by third parties.Information about pharmaceutical products (including products currently in development) which is included in this press release is not intended to constitute an advertisement or medical advice. We focus on Urology, Oncology, Immunology, Nephrology and Neuroscience as prioritized therapeutic areas while advancing new therapeutic areas and discovery research leveraging new technologies/modalities. In January of 2018, Mitobridge was acquired by Astellas Pharma and is now Mitobridge, an Astellas Company. The amount is subject to further true-up based on actual numbers as of the closing date. A number of factors could cause actual results to differ materially from those discussed in the forward-looking statements. held by Mitobridge at the closing. Acquisition Summary (1) Acquiring company: Astellas Pharma Inc. (2) Major shareholders of Mitobridge: MPM Capital, Longwood Funders Fund, Astellas Pharma Inc. (3) Payment: Cash on hand (4). held by Mitobridge at the closing. The acquisition sets the tone for Astellas's further research and development in diseases [] The site uses cookies to provide you with a more responsive and personalized service and to analyze site traffic. held by Mitobridge at the closing. Cautionary Notes The closing of the acquisition is subject to customary regulatory approvals, and is expected to be finalized in the next several weeks. In mitochondria, CoQ lipids are built by an inner membrane-associated, multicomponent, biosynthetic pathway via successive steps of isoprenyl tail polymerization, 4-hydroxybenzoate head-to-tail attachment, and head modification, resulting in the production of CoQ. Mitobridge is discovering and developing small molecule therapeutics that improve mitochondrial functions. We focus on Urology, Oncology, Immunology, Nephrology and Neuroscience as prioritized therapeutic areas while advancing new therapeutic areas and discovery research leveraging new technologies/modalities. Under the 2013 partnership agreements, Astellas and Mitobridge have collaborated to discover and develop compounds that target mitochondrial function. held by Mitobridge at the closing. Astellas is still reviewing the impact of the completion of the acquisition on its financial results for the fiscal year ending March 31, 2018. Astellas Pharma has completed its previously announced acquisition of Mitobridge, a Cambridge, Massachusetts-headquartered company developing small-molecule therapeutics that improve mitochondrial functions, for up to $450 million. Our communications team will respond to verified media requests within 24-48 hours as appropriate. OrsoBio Acquires ACMSD Inhibitor Program to Address Mitochondrial Dysfunction from Mitobridge, an Astellas Company November 2, 2022 Read More News. These statements are based on management's current assumptions and beliefs in light of the information currently available to it and involve known and unknown risks and uncertainties. Astellas shelled out $225 million to acquire 100% of the equity in Mitobridge. (5) Expected timing of closing: Next several weeks, subject to customary regulatory approvals, Overview of Acquired Company Up to $225 million* in future contingent payments based on the advances in clinical programs . Astellas are not responsible for the information or services on this site. held by Mitobridge at the closing. Their scientific founders and advisors include leaders in mitochondrial biology, metabolism and aging with experience in translating novel discoveries into next-generation medicines. As Astellas is a shareholder in Mitobridge, the actual payment by Astellas to Mitobridge shareholders will be $165.5 million. Subsidiaries this chart shows the Distribution of the equity in Mitobridge as division Pulling the trigger on an acquisition option from a partnership deal the two companies formed in 2013 an acquisition from. 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