Download . Download . Famotidine is a competitive histamine-2 (H 2) receptor antagonist that works to inhibit gastric acid secretion.It is commonly used in gastrointestinal conditions related to acid secretion, such as gastric ulcers and gastroesophageal reflux disease (GERD), in adults and children. Pharmaco-omics. 8 Ivermectin itself is a mixture of two avermectins, comprising roughly 90% 5-O-demethyl Structure. Target Sequences. MOL SDF 3D-SDF PDB SMILES InChI. Structure for Magnesium hydroxide (DB09104) Oteseconazole: Magnesium hydroxide can cause a decrease in the absorption of Oteseconazole resulting in a reduced serum concentration and potentially a decrease in efficacy. Generic Name Prazosin DrugBank Accession Number DB00457 Background. After the administration of a dose of 40 mg, its peak plasma concentration of 28 ng/ml is reached 1-2 hours after initial administration with an AUC of about 200 ngh/ml. Ouabain: The serum concentration of Ouabain can be increased when it is combined with Diltiazem. Type. It is not recommended in people MOL SDF 3D-SDF PDB SMILES InChI. 2014 Dec. 25224009. Recently, many studies have evaluated the benefits of this drug in controlling the Similar Structures. Structure for Doxorubicin (DB00997) Oteseconazole: The serum concentration of Doxorubicin can be increased when it is combined with Oteseconazole. Famotidine is a competitive histamine-2 (H 2) receptor antagonist that works to inhibit gastric acid secretion.It is commonly used in gastrointestinal conditions related to acid secretion, such as gastric ulcers and gastroesophageal reflux disease (GERD), in adults and children. This includes aspergillosis, blastomycosis, coccidioidomycosis, histoplasmosis, and paracoccidioidomycosis. Structure. Nystatin, sold under the brandname Mycostatin among others, is an antifungal medication. Oteseconazole: The therapeutic efficacy of Amphotericin B can be decreased when used in combination with Oteseconazole. Similar Structures. 3,10,11,13 Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972. 5,6 The dual action of carvedilol is advantageous in It is taken by mouth. Generic Name Carvedilol DrugBank Accession Number DB01136 Background. Absorption. Structure for Sodium bicarbonate (DB01390) Oteseconazole: Sodium bicarbonate can cause a decrease in the absorption of Oteseconazole resulting in a reduced serum concentration and potentially a decrease in efficacy. The serum concentration of Dasatinib can be increased when it is combined with Oteseconazole. MOL SDF 3D-SDF PDB SMILES InChI. It is a medication used for treating hyperthyroidism, in radiation emergencies, and for protecting the thyroid gland when certain types of radiopharmaceuticals are used. Similar Structures. 9 It is a tertiary amine that can be presented as (E) and (Z) stereoisomers with the (Z) stereoisomer corresponding to cidoxepin.Doxepin commonly produces a 5:1 (E):(Z) racemic mixture. Similar Structures. MOL SDF PDB SMILES InChI. Generic Name Olanzapine DrugBank Accession Number DB00334 Background. Oteseconazole is designed to inhibit fungal CYP51, which is required for fungal cell wall integrity, and this selective interaction is also toxic to fungi, resulting in the inhibition of fungal growth. VIVJOA (oteseconazole) capsules, for oral use . Download . MOL SDF 3D-SDF PDB SMILES InChI. The compound is classified as aromatic due to the presence of a planar ring containing 5H 2 O.The solid is an efflorescent (loses water readily) crystalline substance that dissolves well in water.. Itraconazole, sometimes abbreviated ITZ, is an antifungal medication used to treat a number of fungal infections. This includes fungal infections of the nails and scalp, as well as the skin when antifungal creams have not worked. 3 This drug is an immunosuppressant combined with drugs such as Cyclosporine and corticosteroids to Generic Name Doxepin DrugBank Accession Number DB01142 Background. Olanzapine is a thienobenzodiazepine classified as an atypical or second-generation antipsychotic agent. arrhizus Infection. CS199205_1369764-02-2_Lemborexant_Cato Research Chemicals Inc. - Product No. CS199205 C22H20F2N4O2 410.42 Cas 1369764-02-2 Ouabain: Ouabain may decrease the cardiotoxic activities of Etoposide. For the treatment of recurrent VVC (RVVC) in combination with oteseconazole to reduce the incidence in persons with a history of RVVC who are not of reproductive potential. This includes candidiasis, blastomycosis, coccidiodomycosis, cryptococcosis, histoplasmosis, dermatophytosis, and pityriasis versicolor. The structural formula is Oteseconazole is a white to off-white crystalline powder and is practically insoluble in water within a pH range of 1 to 9 but Initial U.S. Approval: 2022 -----INDICATIONS AND USAGE----- VIVJOA is an azole antifungal indicated to reduce the incidence of . 3D. 3D. VT-1161 Protects Immunosuppressed Mice from Rhizopus arrhizus var. Structure for Etoposide (DB00773) Oteseconazole: The serum concentration of Etoposide can be increased when it is combined with Oteseconazole. Recently, many studies have evaluated the benefits of this drug in controlling the MOL SDF 3D-SDF PDB SMILES InChI. Structure for Sodium bicarbonate (DB01390) Oteseconazole: Sodium bicarbonate can cause a decrease in the absorption of Oteseconazole resulting in a reduced serum concentration and potentially a decrease in efficacy. 8 In a strict sense, doxepin Oteseconazole: The therapeutic efficacy of Amphotericin B can be decreased when used in combination with Oteseconazole. The most common side effects include abnormal liver tests, nausea, vomiting, difficulty breathing, abdominal pain, diarrhea, injection site reactions, headache, low blood potassium and skin rash. Structure for Oteseconazole (DB13055) 1D NMR Search. Ivermectin is a semi-synthetic antiparasitic medication derived from avermectins, a class of highly-active broad-spectrum antiparasitic agents isolated from the fermentation products of Streptomyces avermitilis. Generic Name Ivermectin DrugBank Accession Number DB00602 Background. 3D. The LactMed database contains information on drugs and other chemicals to which breastfeeding mothers may be exposed. 3D. MOL SDF 3D-SDF PDB SMILES InChI. 3D. Download . Similar Structures. Generic Name Nitrofurantoin DrugBank Accession Number DB00698 Background. Oxaliplatin: The risk or severity of adverse effects can be increased when Oxaliplatin is combined with Dasatinib. It includes information on the levels of such substances in breast milk and infant blood, and the possible adverse effects in the nursing infant. Generic Name Nifedipine DrugBank Accession Number DB01115 Background. This includes fungal infections of the nails and scalp, as well as the skin when antifungal creams have not worked. Name. Oteseconazole, also known as VT-1161, is a tetrazole antifungal agent potentially for the treatment of candidal vaginal infection. Structure. Structure for Cimetidine (DB00501) Oteseconazole: Cimetidine can cause a decrease in the absorption of Oteseconazole resulting in a reduced serum concentration and potentially a decrease in efficacy. OTESECONAZOLE. Additionally, the structure as drawn above is the lactam tautomer and indicates the molecule being an N-hydroxy-2-pyridone. 8,9,10 Nitrofurantoin is converted by bacterial nitroreductases to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of DNA, RNA, and protein. NDC Code Structure : 74695 - Mycovia Pharmaceuticals, Inc. 74695-823 - Vivjoa. Griseofulvin is an antifungal medication used to treat a number of types of dermatophytoses (ringworm). Similar Structures. Doxepin is a psychotropic agent with antidepressant and anxiolytic properties. Structure. Structure. Structure and properties. For the treatment of recurrent VVC (RVVC) in combination with oteseconazole to reduce the incidence in persons with a history of RVVC who are not of reproductive potential. Structure. Fluconazole is an antifungal medication used for a number of fungal infections. Apixaban is an oral, direct, and highly selective factor Xa (FXa) inhibitor of both free and bound FXa, as well as prothrombinase, independent of antithrombin III for the prevention and treatment of thromboembolic diseases Label,2.It is marketed under the name Eliquis Label,3.Apixaban was Oxaliplatin: The risk or severity of adverse effects can be increased when Oxaliplatin is combined with Dasatinib. Structure. Download . Sodium thiosulfate is used in gold mining, water treatment, analytical chemistry, the Ouabain: Ouabain may decrease the cardiotoxic activities of Doxorubicin. 16 It is used to manage symptoms of various types of arthritis pain and in familial The LactMed database contains information on drugs and other chemicals to which breastfeeding mothers may be exposed. VIVJOA (oteseconazole) is indicated to reduce the incidence of recurrent vulvovaginal candidiasis (RVVC) in females with a history of RVVC who are NOT of reproductive potential. 3D. 3,10,11,13 Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972. Oteseconazole, also known as VT-1161, is a tetrazole antifungal agent potentially for the treatment of candidal vaginal infection. Similar Structures. Download . If you're a patient at MSK and you need to reach a provider after 5:00 p.m., during the weekend, or on a holiday, call 212-639-2000. Nystatin, sold under the brandname Mycostatin among others, is an antifungal medication. Ranitidine is a commonly used drug, classified as a histamine H2-receptor antagonist, and belongs to the same drug class as cimetidine and famotidine.This drug helps to prevent and treat gastric-acid associated conditions, including ulcers, because of its ability to decrease gastric acid secretion. Hence the classification of ciclopirox as a 2-pyridone antifungal agent. Oteseconazole is an azole antifungal indicated to reduce the incidence of recurrent vulvovaginal candidiasis (RVVC) in females with a history of RVVC who are NOT of reproductive potential. Structure for Cladribine (DB00242) Oteseconazole: The serum concentration of Cladribine can be increased when it is combined with Oteseconazole. Similar Structures. The empirical formula is C 23 H 16 F 7 N 5 O 2. Oteseconazole: The serum concentration of Gefitinib can be increased when it is combined with Oteseconazole. Oteseconazole: The therapeutic efficacy of Oteseconazole can be increased when used in combination with Diltiazem. If you have any questions, contact a member of your healthcare team directly. Similar Structures. All data are derived from the 2 This drug is more resistant to the A renal scan involves the use of radioactive material to examine your kidneys and assess their function. Imidazole is a planar 5-membered ring, that exists in two equivalent tautomeric forms because hydrogen can be bound to one or another nitrogen atom. Structure. VT-1161 dosed once daily or once weekly exhibits potent efficacy in treatment of dermatophytosis in a guinea pig model. Download . Similar Structures. 16 It is used to manage symptoms of various types of arthritis pain and in familial Similar Structures. Imidazole is a highly polar compound, as evidenced by its electric dipole moment of 3.67 D, and is highly soluble in water. This includes aspergillosis, blastomycosis, coccidioidomycosis, histoplasmosis, and paracoccidioidomycosis. Suggested therapeutic alternatives to those drugs are provided, where appropriate. MOL SDF PDB SMILES InChI. Severe side effects may include Friday, October 14, 2022. It is used to treat Candida infections of the skin including diaper rash, thrush, esophageal candidiasis, and vaginal yeast infections. Generic Name Imatinib DrugBank Accession Number DB00619 Background. MOL SDF 3D-SDF PDB SMILES InChI. It is also used to prevent candidiasis in those who are at high risk such as following organ transplantation, low birth weight babies, and those with low blood neutrophil Structure. 3D. Carvedilol is a racemic mixture where the S(-) enantiomer is a beta adrenoceptor blocker and the R(+) enantiomer is both a beta and alpha-1 adrenoceptor blocker. Itraconazole, sometimes abbreviated ITZ, is an antifungal medication used to treat a number of fungal infections. Isavuconazonium sulfate, sold under the brand name Cresemba, is a systemic antifungal medication of the triazole class which is used to treat invasive aspergillosis and mucormycosis.. Similar Structures. Oxamniquine: Interaction Checker; Downloads; Solutions. Mycophenolate mofetil, also known as MMF or CellCept, is a prodrug of mycophenolic acid, and classified as a reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH). Atorvastatin presents a dose-dependent and non-linear pharmacokinetic profile. 3D. MOL SDF 3D-SDF PDB SMILES InChI. Structure. It is a supplement used by people with low dietary intake It is not recommended in people For that purpose, the X-ray crystallographic structure of sterol 14-demethylase enzyme (CYP51) complexed with oteseconazole (PDB entry: 5TZ1; resolution: 2.00 ), was employed . MOL SDF 3D-SDF PDB SMILES InChI. Due to its chemical structure, oteseconazole has a lower affinity for human CYP enzymes as compared to fungal CYP enzymes. Generic Name Amlodipine DrugBank Accession Number DB00381 Background. Download . 5,6 It is currently used to treat heart failure, left ventricular dysfunction, and hypertension. Generic Name Famotidine DrugBank Accession Number DB00927 Background. An enlarged prostate is often responsible for causing bladder neck obstruction. Ouabain: Ouabain may decrease the cardiotoxic activities of Doxorubicin. Download . Common side effects include allergic reactions, nausea, diarrhea, headache, trouble sleeping, and feeling tired. Generic Name Prazosin DrugBank Accession Number DB00457 Background. Additionally, the structure as drawn above is the lactam tautomer and indicates the molecule being an N-hydroxy-2-pyridone. Common side effects include allergic reactions, nausea, diarrhea, headache, trouble sleeping, and feeling tired. Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called dihydropyridine calcium channel blockers.Due to their selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with a lower incidence of 2 The second-generation antipsychotics were introduced in the 90s and quickly gained traction due to their impressive efficacy, reduced risk for extrapyramidal side effects and reduced susceptibility In the maintenance phase, oteseconazole was superior to placebo in the proportion of participants in the intent-to-treat population with 1 culture-verified acute vulvovaginal candidiasis episode through 50 weeks, 5.1% compared with 42.2%, respectively (P<.001). Prazosin, also known as Minipress, is a drug used to treat hypertension.Prazosin is marketed by Pfizer and was initially approved by the FDA in 1988 16.It belongs to the class of drugs known as alpha-1 antagonists Label, 8.. It may also be used to prevent candidiasis in those who are at high risk. Structure. Generic Name Apixaban DrugBank Accession Number DB06605 Background. Structural analyses of Candida albicans sterol 14-demethylase complexed with azole drugs address the molecular basis of azole-mediated inhibition of fungal sterol biosynthesis. Oteseconazole - Mycovia Pharmaceuticals Alternative Names: VIVJOA; SHR-8008; VT-1161 Latest Information Update: 29 Aug 2022 Price : $50 * Buy Profile Adis is an information provider. Griseofulvin is an antifungal medication used to treat a number of types of dermatophytoses (ringworm). Antibacterials are used to treat bacterial infections.Antibiotics are classified generally as beta-lactams, macrolides, quinolones, tetracyclines or aminoglycosides.Their classification within these categories depends on their antimicrobial spectra, pharmacodynamics, and chemical composition. 3D. Nystatin may be used by mouth, in the vagina, or applied to the skin. Prazosin, also known as Minipress, is a drug used to treat hypertension.Prazosin is marketed by Pfizer and was initially approved by the FDA in 1988 16.It belongs to the class of drugs known as alpha-1 antagonists Label, 8.. 4 It is very rapidly absorbed after oral administration. Ouabain: The risk or severity of adverse effects can be increased when Amphotericin B is combined with Ouabain. Generic Name Imatinib DrugBank Accession Number DB00619 Background. Carvedilol is a racemic mixture where the S(-) enantiomer is a beta adrenoceptor blocker and the R(+) enantiomer is both a beta and alpha-1 adrenoceptor blocker. Oral dosage. Mycophenolate mofetil, also known as MMF or CellCept, is a prodrug of mycophenolic acid, and classified as a reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH). It is a supplement used by people with low dietary intake Nitrofurantoin is a nitrofuran antibiotic used to treat uncomplicated urinary tract infections. Imatinib is a small molecule kinase inhibitor that revolutionized the treatment of cancer, particularly chronic myeloid leukemia, in 2001. The molecular weight is 527.39 g/mol. Severe side effects may include Generic Name Doxepin DrugBank Accession Number DB01142 Background. Similar Structures. however, ibrexafungerp is structurally distinct as a semisynthetic derivative of the naturally occurring hemiacetal triterpene glycoside enfumafungin that incorporates a pyridine triazole at position 15 of the core phenanthropyran carboxylic acid ring system and a 2-amino- 2,3,3-trimethyl-butyl ether at position 14 to enhance its antifungal 2,11 Ouabain: The risk or severity of adverse effects can be increased when Amphotericin B is combined with Ouabain. Structure. Accuracy of docking protocol was validated by docking co-crystallized ligand oteseconazole into its binding site. Generic Name Mycophenolate mofetil DrugBank Accession Number DB00688 Background. Ivermectin is a semi-synthetic antiparasitic medication derived from avermectins, a class of highly-active broad-spectrum antiparasitic agents isolated from the fermentation products of Streptomyces avermitilis. Ranitidine is a commonly used drug, classified as a histamine H2-receptor antagonist, and belongs to the same drug class as cimetidine and famotidine.This drug helps to prevent and treat gastric-acid associated conditions, including ulcers, because of its ability to decrease gastric acid secretion. MS/MS Search. Celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is a nonsteroidal anti-inflammatory drug (NSAID) which is known for its decreased risk of causing gastrointestinal bleeding compared to other NSAIDS. 2017 Apr 21. Drug & Food Interactions. 5,6 It is currently used to treat heart failure, left ventricular dysfunction, and hypertension. In some cases, bladder neck obstruction might even be caused by a genetic flaw in the bladder structure or its surrounding muscles and connective tissues. 150 mg PO once daily on days 1, 4, and 7, followed by oteseconazole therapy for 12 weeks. 2,11 2 The second-generation antipsychotics were introduced in the 90s and quickly gained traction due to their impressive efficacy, reduced risk for extrapyramidal side effects and reduced susceptibility Atorvastatin presents a dose-dependent and non-linear pharmacokinetic profile. Download . Imatinib is a small molecule kinase inhibitor that revolutionized the treatment of cancer, particularly chronic myeloid leukemia, in 2001. It may be given by mouth or intravenously.. Common side effects include nausea, diarrhea, abdominal pain, rash, and headache. Generic Name Apixaban DrugBank Accession Number DB06605 Background. Nitrofurantoin is a nitrofuran antibiotic used to treat uncomplicated urinary tract infections. 8 Compared to other H 2 Download . 5H 2 O.The solid is an efflorescent (loses water readily) crystalline substance that dissolves well in water.. 3D. The compound is classified as aromatic due to the presence of a planar ring containing Ouabain: The serum concentration of Ouabain can be increased when it is combined with Diltiazem. Download . Generic Name Ranitidine DrugBank Accession Number DB00863 Background. Oxaliplatin: Gefitinib may decrease the excretion rate of Oxaliplatin which could result in a higher serum level. If specimens for fungal culture are obtained prior to therapy, antifungal therapy may be instituted before the results of the cultures are known. It may be given by mouth or intravenously.. Common side effects include nausea, diarrhea, abdominal pain, rash, and headache. Prolonged use of certain antibacterials can decrease the number of enteric bacteria, which may Generic Name Ivermectin DrugBank Accession Number DB00602 Background. Generic Name Carvedilol DrugBank Accession Number DB01136 Background. Adults. Structure for Doxorubicin (DB00997) Oteseconazole: The serum concentration of Doxorubicin can be increased when it is combined with Oteseconazole. 3D. The serum concentration of Dasatinib can be increased when it is combined with Oteseconazole. Suggested therapeutic alternatives to those drugs are provided, where appropriate. Language. Chemical Structure Oteseconazole CAS# 1340593-59-0 Instruction Theoretical Analysis Hodoodo Cat#: H319588 Name: Oteseconazole CAS#: 1340593-59-0 Chemical Formula: C23H16F7N5O2 Exact Mass: 527.1192 Molecular Weight: 527.4 Elemental Analysis: C, 52.38; H, 3.06; F, 25.22; N, 13.28; O, 6.07 Price and Availability Technical data Chemical Structure. Hence the classification of ciclopirox as a 2-pyridone antifungal agent. Potassium iodide is a chemical compound, medication, and dietary supplement. 3 This drug is an immunosuppressant combined with drugs such as Cyclosporine and corticosteroids to 8 Compared to other H 2 Oxamniquine: Download . Sodium thiosulfate is used in gold mining, water treatment, analytical chemistry, the 3D. Final gross price and currency may vary according to local VAT and billing address. Advanced Search. MOL SDF 3D-SDF PDB SMILES InChI. 3D. Prolonged use of certain antibacterials can decrease the number of enteric bacteria, which may Download . Structure. Similar Structures. Ouabain: All data are derived from the Olanzapine is a thienobenzodiazepine classified as an atypical or second-generation antipsychotic agent. Generic Name Ranitidine DrugBank Accession Number DB00863 Background. 3D. In the third world it is also used for treating skin sporotrichosis and phycomycosis. Oteseconazole is an azole metalloenzyme inhibitor targeting the fungal sterol, 14 demethylase (CYP51), an enzyme that catalyzes an early step in the biosynthetic pathway of ergosterol, a sterol required for fungal cell membrane formation and integrity. Generic Name Mycophenolate mofetil DrugBank Accession Number DB00688 Background. Download . If you have any questions, contact a member of your healthcare team directly. Generic Name Nitrofurantoin DrugBank Accession Number DB00698 Background. We do not sell or distribute actual drugs. Adults. MOL SDF 3D-SDF PDB SMILES InChI. Generic Name Celecoxib DrugBank Accession Number DB00482 Background. Structure and properties. VT-1161 Protects Immunosuppressed Mice from Rhizopus arrhizus var. Structure for Cladribine (DB00242) Oteseconazole: The serum concentration of Cladribine can be increased when it is combined with Oteseconazole. Molecular Weight. Download . Structure. Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to nicardipine. Similar Structures. The prostate is a small gland in the male reproductive system. It is a medication used for treating hyperthyroidism, in radiation emergencies, and for protecting the thyroid gland when certain types of radiopharmaceuticals are used. 2 This drug is more resistant to the It is used to treat Candida infections of the skin including diaper rash, thrush, esophageal candidiasis, and vaginal yeast infections. Ciclopirox is used clinically as ciclopirox olamine, the olamine salt of ciclopirox. MOL SDF 3D-SDF PDB SMILES InChI.
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